The Vergina Hotel Thessaloniki is located in city center. The main market area is within five minutes' walk of the hotel, and guests will also be able to walk to the Byzantine cathedral and the famous White Tower. The Vergina Hotel Thessaloniki is 14 km from the hotel. It is less than 5 minutes from the hotel to the main railway station, and an equal distance for guests to reach the port area for ferry and cruise ship access.

There are 133 rooms at the Vergina Hotel Thessaloniki. Rooms are decorated along a warm and contemporary theme. All rooms have their own private balconies. Other amenities include individualized heating and cooling, satellite television service, radio alarm clocks, direct dial telephones, and en suite bathrooms with hair dryers.

The Vergina Hotel Thessaloniki is a three star business and leisure property with a 24 hour reception desk. Free wireless Internet access is provided throughout the property, and the reception desk is able to offer guests basic business support services. There is an on site restaurant offering traditional Grecian foods, and the lounge bar serves traditional as well as exotic cocktails. Parking is available on site for a small fee.